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quinupristin/dalfopristin will enhance the level or impact of ivacaftor by impacting hepatic/intestinal enzyme CYP3A4 metabolism.quinupristin/dalfopristin will improve the stage or impact of donepezil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unidentified.Ideal experiments executed to this point haven't demonstra